ONTOLOGY Type ID Description GeneRatio BgRatio pvalue p.adjust qvalue Count GO:0051607 BP GO:0051607 defense response to virus 63/272 238/18670 4.04E-62 1.28E-58 1.04E-58 63 GO:0009615 BP GO:0009615 response to virus 67/272 326/18670 3.63E-58 5.77E-55 4.68E-55 67 GO:0034340 BP GO:0034340 response to type I interferon 43/272 99/18670 3.69E-53 3.92E-50 3.18E-50 43 GO:0060337 BP GO:0060337 type I interferon signaling pathway 42/272 95/18670 2.45E-52 1.56E-49 1.26E-49 42 GO:0071357 BP GO:0071357 cellular response to type I interferon 42/272 95/18670 2.45E-52 1.56E-49 1.26E-49 42 GO:0034341 BP GO:0034341 response to interferon-gamma 51/272 199/18670 2.70E-49 1.43E-46 1.16E-46 51 GO:0071346 BP GO:0071346 cellular response to interferon-gamma 44/272 180/18670 1.64E-41 7.47E-39 6.06E-39 44 GO:0060333 BP GO:0060333 interferon-gamma-mediated signaling pathway 35/272 91/18670 5.04E-41 2.00E-38 1.63E-38 35 GO:0048525 BP GO:0048525 negative regulation of viral process 29/272 99/18670 4.32E-30 1.53E-27 1.24E-27 29 GO:1903900 BP GO:1903900 regulation of viral life cycle 33/272 149/18670 1.01E-29 3.22E-27 2.61E-27 33 GO:1903901 BP GO:1903901 negative regulation of viral life cycle 27/272 85/18670 3.64E-29 1.05E-26 8.54E-27 27 GO:0043900 BP GO:0043900 regulation of multi-organism process 46/272 405/18670 9.08E-28 2.41E-25 1.95E-25 46 GO:0043901 BP GO:0043901 negative regulation of multi-organism process 33/272 171/18670 1.23E-27 3.00E-25 2.44E-25 33 GO:0050792 BP GO:0050792 regulation of viral process 35/272 208/18670 4.01E-27 9.11E-25 7.39E-25 35 GO:0043903 BP GO:0043903 "regulation of symbiosis, encompassing mutualism through parasitism" 35/272 222/18670 4.03E-26 8.54E-24 6.93E-24 35 GO:0045069 BP GO:0045069 regulation of viral genome replication 25/272 95/18670 8.98E-25 1.79E-22 1.45E-22 25 GO:0045071 BP GO:0045071 negative regulation of viral genome replication 21/272 59/18670 3.93E-24 7.35E-22 5.96E-22 21 GO:0045088 BP GO:0045088 regulation of innate immune response 44/272 452/18670 8.37E-24 1.48E-21 1.20E-21 44 GO:0019079 BP GO:0019079 viral genome replication 26/272 122/18670 3.80E-23 6.35E-21 5.15E-21 26 GO:0019058 BP GO:0019058 viral life cycle 37/272 328/18670 2.56E-22 4.07E-20 3.30E-20 37 GO:0032479 BP GO:0032479 regulation of type I interferon production 22/272 126/18670 8.90E-18 1.35E-15 1.09E-15 22 GO:0032606 BP GO:0032606 type I interferon production 22/272 128/18670 1.27E-17 1.83E-15 1.49E-15 22 GO:0035456 BP GO:0035456 response to interferon-beta 13/272 28/18670 3.08E-17 4.26E-15 3.46E-15 13 GO:0060759 BP GO:0060759 regulation of response to cytokine stimulus 24/272 190/18670 6.09E-16 8.07E-14 6.55E-14 24 GO:0045824 BP GO:0045824 negative regulation of innate immune response 15/272 59/18670 4.32E-15 5.50E-13 4.46E-13 15 GO:0001959 BP GO:0001959 regulation of cytokine-mediated signaling pathway 22/272 177/18670 1.46E-14 1.79E-12 1.45E-12 22 GO:0045089 BP GO:0045089 positive regulation of innate immune response 30/272 381/18670 5.58E-14 6.57E-12 5.33E-12 30 GO:0035455 BP GO:0035455 response to interferon-alpha 10/272 21/18670 1.12E-13 1.27E-11 1.03E-11 10 GO:0002483 BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 9/272 15/18670 1.20E-13 1.27E-11 1.03E-11 9 GO:0019885 BP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 9/272 15/18670 1.20E-13 1.27E-11 1.03E-11 9 GO:0002697 BP GO:0002697 regulation of immune effector process 32/272 458/18670 2.08E-13 2.14E-11 1.73E-11 32 GO:0001819 BP GO:0001819 positive regulation of cytokine production 31/272 464/18670 1.65E-12 1.64E-10 1.33E-10 31 GO:0042590 BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 14/272 79/18670 7.42E-12 7.15E-10 5.80E-10 14 GO:0046596 BP GO:0046596 regulation of viral entry into host cell 10/272 30/18670 8.49E-12 7.94E-10 6.44E-10 10 GO:0002474 BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 15/272 96/18670 8.76E-12 7.96E-10 6.46E-10 15 GO:0007249 BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 23/272 269/18670 1.05E-11 9.25E-10 7.50E-10 23 GO:0019883 BP GO:0019883 antigen processing and presentation of endogenous antigen 9/272 22/18670 1.09E-11 9.39E-10 7.62E-10 9 GO:0002831 BP GO:0002831 regulation of response to biotic stimulus 17/272 139/18670 2.03E-11 1.70E-09 1.38E-09 17 GO:0070555 BP GO:0070555 response to interleukin-1 20/272 207/18670 2.69E-11 2.19E-09 1.78E-09 20 GO:0034612 BP GO:0034612 response to tumor necrosis factor 24/272 312/18670 3.42E-11 2.72E-09 2.20E-09 24 GO:0050688 BP GO:0050688 regulation of defense response to virus 13/272 73/18670 3.96E-11 3.07E-09 2.49E-09 13 GO:0032480 BP GO:0032480 negative regulation of type I interferon production 11/272 46/18670 4.36E-11 3.24E-09 2.63E-09 11 GO:0043122 BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 21/272 237/18670 4.38E-11 3.24E-09 2.63E-09 21 GO:0002479 BP GO:0002479 "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent" 13/272 75/18670 5.66E-11 4.09E-09 3.32E-09 13 GO:0050777 BP GO:0050777 negative regulation of immune response 17/272 150/18670 6.95E-11 4.91E-09 3.99E-09 17 GO:0071347 BP GO:0071347 cellular response to interleukin-1 18/272 179/18670 1.41E-10 9.72E-09 7.88E-09 18 GO:0002683 BP GO:0002683 negative regulation of immune system process 28/272 463/18670 2.13E-10 1.44E-08 1.17E-08 28 GO:0051091 BP GO:0051091 positive regulation of DNA-binding transcription factor activity 21/272 261/18670 2.65E-10 1.76E-08 1.43E-08 21 GO:0002456 BP GO:0002456 T cell mediated immunity 14/272 106/18670 4.44E-10 2.88E-08 2.34E-08 14 GO:0000209 BP GO:0000209 protein polyubiquitination 22/272 310/18670 1.07E-09 6.81E-08 5.53E-08 22 GO:0002475 BP GO:0002475 antigen processing and presentation via MHC class Ib 7/272 16/18670 1.32E-09 8.12E-08 6.59E-08 7 GO:0002237 BP GO:0002237 response to molecule of bacterial origin 23/272 343/18670 1.33E-09 8.12E-08 6.59E-08 23 GO:0043123 BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 17/272 183/18670 1.58E-09 9.51E-08 7.71E-08 17 GO:0002218 BP GO:0002218 activation of innate immune response 22/272 319/18670 1.83E-09 1.08E-07 8.73E-08 22 GO:0071356 BP GO:0071356 cellular response to tumor necrosis factor 21/272 291/18670 1.93E-09 1.11E-07 9.03E-08 21 GO:0001818 BP GO:0001818 negative regulation of cytokine production 21/272 296/18670 2.61E-09 1.48E-07 1.20E-07 21 GO:0002758 BP GO:0002758 innate immune response-activating signal transduction 21/272 298/18670 2.95E-09 1.64E-07 1.33E-07 21 GO:0032496 BP GO:0032496 response to lipopolysaccharide 22/272 330/18670 3.43E-09 1.88E-07 1.52E-07 22 GO:0051090 BP GO:0051090 regulation of DNA-binding transcription factor activity 25/272 432/18670 5.10E-09 2.75E-07 2.23E-07 25 GO:0046597 BP GO:0046597 negative regulation of viral entry into host cell 7/272 19/18670 5.60E-09 2.97E-07 2.41E-07 7 GO:0019882 BP GO:0019882 antigen processing and presentation 18/272 226/18670 6.12E-09 3.19E-07 2.59E-07 18 GO:0098586 BP GO:0098586 cellular response to virus 10/272 56/18670 7.21E-09 3.70E-07 3.00E-07 10 GO:0035458 BP GO:0035458 cellular response to interferon-beta 7/272 20/18670 8.50E-09 4.29E-07 3.48E-07 7 GO:0060760 BP GO:0060760 positive regulation of response to cytokine stimulus 10/272 57/18670 8.63E-09 4.29E-07 3.48E-07 10 GO:2000116 BP GO:2000116 regulation of cysteine-type endopeptidase activity 18/272 239/18670 1.47E-08 7.19E-07 5.84E-07 18 GO:0048002 BP GO:0048002 antigen processing and presentation of peptide antigen 16/272 189/18670 1.84E-08 8.80E-07 7.14E-07 16 GO:0001914 BP GO:0001914 regulation of T cell mediated cytotoxicity 8/272 33/18670 1.85E-08 8.80E-07 7.14E-07 8 GO:0002711 BP GO:0002711 positive regulation of T cell mediated immunity 9/272 48/18670 2.64E-08 1.24E-06 1.00E-06 9 GO:0001913 BP GO:0001913 T cell mediated cytotoxicity 9/272 49/18670 3.20E-08 1.47E-06 1.20E-06 9 GO:0002221 BP GO:0002221 pattern recognition receptor signaling pathway 16/272 197/18670 3.31E-08 1.50E-06 1.22E-06 16 GO:0051092 BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 14/272 149/18670 3.91E-08 1.75E-06 1.42E-06 14 GO:0002478 BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 15/272 175/18670 4.38E-08 1.93E-06 1.57E-06 15 GO:0071222 BP GO:0071222 cellular response to lipopolysaccharide 16/272 205/18670 5.78E-08 2.52E-06 2.04E-06 16 GO:0001916 BP GO:0001916 positive regulation of T cell mediated cytotoxicity 7/272 26/18670 6.69E-08 2.85E-06 2.31E-06 7 GO:0002709 BP GO:0002709 regulation of T cell mediated immunity 10/272 70/18670 6.71E-08 2.85E-06 2.31E-06 10 GO:0007259 BP GO:0007259 JAK-STAT cascade 14/272 156/18670 6.99E-08 2.92E-06 2.37E-06 14 GO:0052548 BP GO:0052548 regulation of endopeptidase activity 23/272 425/18670 7.35E-08 3.01E-06 2.44E-06 23 GO:0019884 BP GO:0019884 antigen processing and presentation of exogenous antigen 15/272 182/18670 7.38E-08 3.01E-06 2.44E-06 15 GO:0051701 BP GO:0051701 interaction with host 16/272 209/18670 7.56E-08 3.04E-06 2.47E-06 16 GO:0031348 BP GO:0031348 negative regulation of defense response 17/272 239/18670 8.60E-08 3.42E-06 2.77E-06 17 GO:0071219 BP GO:0071219 cellular response to molecule of bacterial origin 16/272 212/18670 9.21E-08 3.62E-06 2.93E-06 16 GO:0002819 BP GO:0002819 regulation of adaptive immune response 14/272 160/18670 9.60E-08 3.72E-06 3.02E-06 14 GO:0043281 BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 16/272 215/18670 1.12E-07 4.28E-06 3.48E-06 16 GO:0097696 BP GO:0097696 STAT cascade 14/272 166/18670 1.52E-07 5.75E-06 4.67E-06 14 GO:0033209 BP GO:0033209 tumor necrosis factor-mediated signaling pathway 14/272 167/18670 1.64E-07 6.13E-06 4.97E-06 14 GO:0032481 BP GO:0032481 positive regulation of type I interferon production 10/272 77/18670 1.70E-07 6.28E-06 5.09E-06 10 GO:0031341 BP GO:0031341 regulation of cell killing 11/272 98/18670 1.87E-07 6.85E-06 5.56E-06 11 GO:0001910 BP GO:0001910 regulation of leukocyte mediated cytotoxicity 10/272 78/18670 1.92E-07 6.95E-06 5.64E-06 10 GO:0032607 BP GO:0032607 interferon-alpha production 7/272 30/18670 1.97E-07 7.04E-06 5.71E-06 7 GO:0052547 BP GO:0052547 regulation of peptidase activity 23/272 452/18670 2.21E-07 7.82E-06 6.34E-06 23 GO:0002753 BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 9/272 62/18670 2.68E-07 9.35E-06 7.59E-06 9 GO:0002703 BP GO:0002703 regulation of leukocyte mediated immunity 15/272 201/18670 2.71E-07 9.36E-06 7.59E-06 15 GO:0032103 BP GO:0032103 positive regulation of response to external stimulus 19/272 323/18670 2.94E-07 1.01E-05 8.17E-06 19 GO:0002460 BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 20/272 361/18670 3.71E-07 1.26E-05 1.02E-05 20 GO:0071216 BP GO:0071216 cellular response to biotic stimulus 16/272 236/18670 3.98E-07 1.33E-05 1.08E-05 16 GO:0001909 BP GO:0001909 leukocyte mediated cytotoxicity 11/272 107/18670 4.62E-07 1.53E-05 1.24E-05 11 GO:0001961 BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 8/272 50/18670 5.79E-07 1.88E-05 1.52E-05 8 GO:0032608 BP GO:0032608 interferon-beta production 8/272 50/18670 5.79E-07 1.88E-05 1.52E-05 8 GO:0060338 BP GO:0060338 regulation of type I interferon-mediated signaling pathway 7/272 35/18670 6.12E-07 1.93E-05 1.57E-05 7 GO:0030260 BP GO:0030260 entry into host cell 12/272 134/18670 6.25E-07 1.93E-05 1.57E-05 12 GO:0044409 BP GO:0044409 entry into host 12/272 134/18670 6.25E-07 1.93E-05 1.57E-05 12 GO:0051806 BP GO:0051806 entry into cell of other organism involved in symbiotic interaction 12/272 134/18670 6.25E-07 1.93E-05 1.57E-05 12 GO:0051828 BP GO:0051828 entry into other organism involved in symbiotic interaction 12/272 134/18670 6.25E-07 1.93E-05 1.57E-05 12 GO:0050691 BP GO:0050691 regulation of defense response to virus by host 7/272 37/18670 9.14E-07 2.79E-05 2.27E-05 7 GO:0046135 BP GO:0046135 pyrimidine nucleoside catabolic process 6/272 24/18670 9.77E-07 2.96E-05 2.40E-05 6 GO:0002449 BP GO:0002449 lymphocyte mediated immunity 19/272 352/18670 1.08E-06 3.25E-05 2.63E-05 19 GO:0045953 BP GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 5/272 14/18670 1.14E-06 3.38E-05 2.74E-05 5 GO:0060330 BP GO:0060330 regulation of response to interferon-gamma 6/272 25/18670 1.27E-06 3.70E-05 3.01E-05 6 GO:0060334 BP GO:0060334 regulation of interferon-gamma-mediated signaling pathway 6/272 25/18670 1.27E-06 3.70E-05 3.01E-05 6 GO:0002822 BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 12/272 145/18670 1.45E-06 4.20E-05 3.41E-05 12 GO:0046718 BP GO:0046718 viral entry into host cell 11/272 121/18670 1.59E-06 4.55E-05 3.69E-05 11 GO:0002230 BP GO:0002230 positive regulation of defense response to virus by host 6/272 26/18670 1.63E-06 4.63E-05 3.76E-05 6 GO:0050852 BP GO:0050852 T cell receptor signaling pathway 14/272 202/18670 1.65E-06 4.64E-05 3.77E-05 14 GO:0002716 BP GO:0002716 negative regulation of natural killer cell mediated immunity 5/272 15/18670 1.69E-06 4.66E-05 3.78E-05 5 GO:1902187 BP GO:1902187 negative regulation of viral release from host cell 5/272 15/18670 1.69E-06 4.66E-05 3.78E-05 5 GO:0002706 BP GO:0002706 regulation of lymphocyte mediated immunity 12/272 149/18670 1.94E-06 5.32E-05 4.31E-05 12 GO:0002824 BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 10/272 100/18670 2.00E-06 5.38E-05 4.36E-05 10 GO:0070498 BP GO:0070498 interleukin-1-mediated signaling pathway 10/272 100/18670 2.00E-06 5.38E-05 4.36E-05 10 GO:0039528 BP GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 6/272 27/18670 2.07E-06 5.53E-05 4.49E-05 6 GO:0010950 BP GO:0010950 positive regulation of endopeptidase activity 13/272 178/18670 2.18E-06 5.77E-05 4.68E-05 13 GO:0032647 BP GO:0032647 regulation of interferon-alpha production 6/272 28/18670 2.60E-06 6.84E-05 5.55E-05 6 GO:0002821 BP GO:0002821 positive regulation of adaptive immune response 10/272 105/18670 3.12E-06 8.14E-05 6.60E-05 10 GO:0002699 BP GO:0002699 positive regulation of immune effector process 14/272 216/18670 3.63E-06 9.37E-05 7.61E-05 14 GO:0002718 BP GO:0002718 regulation of cytokine production involved in immune response 9/272 84/18670 3.67E-06 9.42E-05 7.64E-05 9 GO:0006919 BP GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 9/272 86/18670 4.47E-06 0.000113834 9.24E-05 9 GO:0001911 BP GO:0001911 negative regulation of leukocyte mediated cytotoxicity 5/272 18/18670 4.64E-06 0.000117126 9.50E-05 5 GO:1902186 BP GO:1902186 regulation of viral release from host cell 6/272 31/18670 4.91E-06 0.000122842 9.97E-05 6 GO:0032648 BP GO:0032648 regulation of interferon-beta production 7/272 48/18670 5.70E-06 0.000141587 0.000114872 7 GO:0031343 BP GO:0031343 positive regulation of cell killing 8/272 68/18670 6.35E-06 0.000156654 0.000127096 8 GO:0010952 BP GO:0010952 positive regulation of peptidase activity 13/272 197/18670 6.66E-06 0.000162917 0.000132178 13 GO:0001906 BP GO:0001906 cell killing 12/272 168/18670 6.76E-06 0.000164033 0.000133083 12 GO:0039530 BP GO:0039530 MDA-5 signaling pathway 4/272 10/18670 8.64E-06 0.00020655 0.000167578 4 GO:0009164 BP GO:0009164 nucleoside catabolic process 6/272 34/18670 8.64E-06 0.00020655 0.000167578 6 GO:0002224 BP GO:0002224 toll-like receptor signaling pathway 11/272 146/18670 9.88E-06 0.000234567 0.000190309 11 GO:0019076 BP GO:0019076 viral release from host cell 6/272 35/18670 1.03E-05 0.000235588 0.000191138 6 GO:0035890 BP GO:0035890 exit from host 6/272 35/18670 1.03E-05 0.000235588 0.000191138 6 GO:0035891 BP GO:0035891 exit from host cell 6/272 35/18670 1.03E-05 0.000235588 0.000191138 6 GO:0052126 BP GO:0052126 movement in host environment 6/272 35/18670 1.03E-05 0.000235588 0.000191138 6 GO:0052192 BP GO:0052192 movement in environment of other organism involved in symbiotic interaction 6/272 35/18670 1.03E-05 0.000235588 0.000191138 6 GO:0002698 BP GO:0002698 negative regulation of immune effector process 10/272 120/18670 1.04E-05 0.000235588 0.000191138 10 GO:2001056 BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 11/272 149/18670 1.20E-05 0.000270453 0.000219424 11 GO:0050663 BP GO:0050663 cytokine secretion 14/272 240/18670 1.21E-05 0.000271872 0.000220575 14 GO:0002720 BP GO:0002720 positive regulation of cytokine production involved in immune response 7/272 54/18670 1.27E-05 0.000282958 0.000229569 7 GO:0031342 BP GO:0031342 negative regulation of cell killing 5/272 22/18670 1.36E-05 0.000298231 0.000241961 5 GO:0032727 BP GO:0032727 positive regulation of interferon-alpha production 5/272 22/18670 1.36E-05 0.000298231 0.000241961 5 GO:0050729 BP GO:0050729 positive regulation of inflammatory response 11/272 153/18670 1.54E-05 0.000335478 0.00027218 11 GO:0038061 BP GO:0038061 NIK/NF-kappaB signaling 12/272 183/18670 1.61E-05 0.000347888 0.000282248 12 GO:0001912 BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 7/272 56/18670 1.63E-05 0.000349249 0.000283353 7 GO:0002367 BP GO:0002367 cytokine production involved in immune response 9/272 102/18670 1.82E-05 0.000388409 0.000315124 9 GO:0072529 BP GO:0072529 pyrimidine-containing compound catabolic process 6/272 39/18670 1.97E-05 0.000417973 0.00033911 6 GO:0032897 BP GO:0032897 negative regulation of viral transcription 5/272 24/18670 2.14E-05 0.000451333 0.000366175 5 GO:0002708 BP GO:0002708 positive regulation of lymphocyte mediated immunity 9/272 105/18670 2.30E-05 0.000480936 0.000390193 9 GO:1903706 BP GO:1903706 regulation of hemopoiesis 20/272 475/18670 2.32E-05 0.00048229 0.000391292 20 GO:0097193 BP GO:0097193 intrinsic apoptotic signaling pathway 15/272 289/18670 2.37E-05 0.000489255 0.000396943 15 GO:0043280 BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 10/272 132/18670 2.39E-05 0.000491005 0.000398363 10 GO:0002705 BP GO:0002705 positive regulation of leukocyte mediated immunity 10/272 133/18670 2.56E-05 0.000518494 0.000420665 10 GO:0045862 BP GO:0045862 positive regulation of proteolysis 17/272 363/18670 2.56E-05 0.000518494 0.000420665 17 GO:0002507 BP GO:0002507 tolerance induction 5/272 25/18670 2.65E-05 0.000532781 0.000432256 5 GO:2001233 BP GO:2001233 regulation of apoptotic signaling pathway 18/272 406/18670 3.06E-05 0.000611684 0.000496272 18 GO:0050727 BP GO:0050727 regulation of inflammatory response 20/272 485/18670 3.12E-05 0.000619444 0.000502568 20 GO:0002244 BP GO:0002244 hematopoietic progenitor cell differentiation 11/272 166/18670 3.29E-05 0.000650595 0.000527841 11 GO:1901658 BP GO:1901658 glycosyl compound catabolic process 6/272 43/18670 3.51E-05 0.000688728 0.000558779 6 GO:0007260 BP GO:0007260 tyrosine phosphorylation of STAT protein 8/272 86/18670 3.64E-05 0.000710024 0.000576057 8 GO:0002700 BP GO:0002700 regulation of production of molecular mediator of immune response 10/272 139/18670 3.74E-05 0.000724627 0.000587905 10 GO:0070234 BP GO:0070234 positive regulation of T cell apoptotic process 4/272 14/18670 3.93E-05 0.000757743 0.000614773 4 GO:0032196 BP GO:0032196 transposition 5/272 28/18670 4.72E-05 0.000905108 0.000734333 5 GO:2000736 BP GO:2000736 regulation of stem cell differentiation 9/272 116/18670 5.07E-05 0.000966353 0.000784022 9 GO:0060339 BP GO:0060339 negative regulation of type I interferon-mediated signaling pathway 4/272 15/18670 5.30E-05 0.000997294 0.000809125 4 GO:2001185 BP GO:2001185 "regulation of CD8-positive, alpha-beta T cell activation" 4/272 15/18670 5.30E-05 0.000997294 0.000809125 4 GO:0050851 BP GO:0050851 antigen receptor-mediated signaling pathway 15/272 316/18670 6.59E-05 0.001228568 0.000996762 15 GO:0030522 BP GO:0030522 intracellular receptor signaling pathway 14/272 280/18670 6.63E-05 0.001228568 0.000996762 14 GO:0044764 BP GO:0044764 multi-organism cellular process 6/272 48/18670 6.65E-05 0.001228568 0.000996762 6 GO:0032728 BP GO:0032728 positive regulation of interferon-beta production 5/272 30/18670 6.69E-05 0.001229674 0.00099766 5 GO:0002704 BP GO:0002704 negative regulation of leukocyte mediated immunity 6/272 49/18670 7.48E-05 0.001359345 0.001102865 6 GO:0032757 BP GO:0032757 positive regulation of interleukin-8 production 6/272 49/18670 7.48E-05 0.001359345 0.001102865 6 GO:0034656 BP GO:0034656 nucleobase-containing small molecule catabolic process 6/272 50/18670 8.40E-05 0.001517352 0.001231059 6 GO:1902036 BP GO:1902036 regulation of hematopoietic stem cell differentiation 7/272 72/18670 8.47E-05 0.001521499 0.001234424 7 GO:0071360 BP GO:0071360 cellular response to exogenous dsRNA 4/272 17/18670 9.03E-05 0.001613435 0.001309014 4 GO:2000027 BP GO:2000027 regulation of animal organ morphogenesis 13/272 253/18670 9.16E-05 0.00162808 0.001320895 13 GO:0006213 BP GO:0006213 pyrimidine nucleoside metabolic process 6/272 51/18670 9.40E-05 0.001661114 0.001347696 6 GO:0001960 BP GO:0001960 negative regulation of cytokine-mediated signaling pathway 7/272 75/18670 0.000109951 0.001931737 0.001567259 7 GO:0070230 BP GO:0070230 positive regulation of lymphocyte apoptotic process 4/272 18/18670 0.000114789 0.002000192 0.001622797 4 GO:0097191 BP GO:0097191 extrinsic apoptotic signaling pathway 12/272 224/18670 0.000115105 0.002000192 0.001622797 12 GO:0043331 BP GO:0043331 response to dsRNA 6/272 53/18670 0.000116978 0.002021677 0.001640229 6 GO:0032652 BP GO:0032652 regulation of interleukin-1 production 8/272 103/18670 0.000131829 0.002266026 0.001838474 8 GO:1903555 BP GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 10/272 163/18670 0.000142368 0.00243403 0.001974779 10 GO:0042110 BP GO:0042110 T cell activation 18/272 464/18670 0.00016716 0.002842615 0.002306273 18 GO:0039529 BP GO:0039529 RIG-I signaling pathway 4/272 20/18670 0.000177625 0.003004511 0.002437622 4 GO:0060761 BP GO:0060761 negative regulation of response to cytokine stimulus 7/272 81/18670 0.000178864 0.003009455 0.002441633 7 GO:0071706 BP GO:0071706 tumor necrosis factor superfamily cytokine production 10/272 168/18670 0.000182298 0.003051092 0.002475414 10 GO:0031663 BP GO:0031663 lipopolysaccharide-mediated signaling pathway 6/272 58/18670 0.000194079 0.003231256 0.002621585 6 GO:0042509 BP GO:0042509 regulation of tyrosine phosphorylation of STAT protein 7/272 83/18670 0.000208362 0.003433122 0.002785363 7 GO:0060218 BP GO:0060218 hematopoietic stem cell differentiation 7/272 83/18670 0.000208362 0.003433122 0.002785363 7 GO:0002707 BP GO:0002707 negative regulation of lymphocyte mediated immunity 5/272 38/18670 0.000214258 0.003512057 0.002849405 5 GO:0016553 BP GO:0016553 base conversion or substitution editing 4/272 21/18670 0.000216917 0.003537419 0.002869982 4 GO:0050863 BP GO:0050863 regulation of T cell activation 14/272 314/18670 0.000220542 0.00357818 0.002903052 14 GO:1901532 BP GO:1901532 regulation of hematopoietic progenitor cell differentiation 7/272 85/18670 0.000241666 0.00390101 0.003164971 7 GO:0032609 BP GO:0032609 interferon-gamma production 8/272 113/18670 0.000250414 0.004021798 0.003262968 8 GO:0010803 BP GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 6/272 61/18670 0.00025672 0.004081846 0.003311686 6 GO:1903902 BP GO:1903902 positive regulation of viral life cycle 6/272 61/18670 0.00025672 0.004081846 0.003311686 6 GO:0032069 BP GO:0032069 regulation of nuclease activity 4/272 22/18670 0.000262099 0.004105789 0.003331112 4 GO:0071359 BP GO:0071359 cellular response to dsRNA 4/272 22/18670 0.000262099 0.004105789 0.003331112 4 GO:0072643 BP GO:0072643 interferon-gamma secretion 4/272 22/18670 0.000262099 0.004105789 0.003331112 4 GO:0050707 BP GO:0050707 regulation of cytokine secretion 11/272 210/18670 0.000268072 0.004178776 0.003390328 11 GO:0032612 BP GO:0032612 interleukin-1 production 8/272 115/18670 0.000282315 0.00437932 0.003553033 8 GO:0051250 BP GO:0051250 negative regulation of lymphocyte activation 9/272 146/18670 0.00029455 0.004546943 0.003689029 9 GO:2001235 BP GO:2001235 positive regulation of apoptotic signaling pathway 10/272 179/18670 0.000304132 0.004672179 0.003790635 10 GO:0010528 BP GO:0010528 regulation of transposition 4/272 23/18670 0.000313663 0.004749757 0.003853576 4 GO:0010529 BP GO:0010529 negative regulation of transposition 4/272 23/18670 0.000313663 0.004749757 0.003853576 4 GO:0036037 BP GO:0036037 "CD8-positive, alpha-beta T cell activation" 4/272 23/18670 0.000313663 0.004749757 0.003853576 4 GO:0046427 BP GO:0046427 positive regulation of JAK-STAT cascade 7/272 89/18670 0.000321123 0.004839671 0.003926526 7 GO:0034058 BP GO:0034058 endosomal vesicle fusion 3/272 10/18670 0.000340215 0.005103224 0.004140351 3 GO:0032651 BP GO:0032651 regulation of interleukin-1 beta production 7/272 90/18670 0.000343941 0.005110893 0.004146573 7 GO:0071674 BP GO:0071674 mononuclear cell migration 7/272 90/18670 0.000343941 0.005110893 0.004146573 7 GO:0035567 BP GO:0035567 non-canonical Wnt signaling pathway 9/272 150/18670 0.00035968 0.005319916 0.004316158 9 GO:0034162 BP GO:0034162 toll-like receptor 9 signaling pathway 4/272 24/18670 0.00037211 0.005453034 0.00442416 4 GO:0042832 BP GO:0042832 defense response to protozoan 4/272 24/18670 0.00037211 0.005453034 0.00442416 4 GO:1904894 BP GO:1904894 positive regulation of STAT cascade 7/272 92/18670 0.000393471 0.005713421 0.004635417 7 GO:2000117 BP GO:2000117 negative regulation of cysteine-type endopeptidase activity 7/272 92/18670 0.000393471 0.005713421 0.004635417 7 GO:0032675 BP GO:0032675 regulation of interleukin-6 production 9/272 152/18670 0.000396449 0.005730486 0.004649262 9 GO:0070663 BP GO:0070663 regulation of leukocyte proliferation 11/272 222/18670 0.000430212 0.006184322 0.005017469 11 GO:0042269 BP GO:0042269 regulation of natural killer cell mediated cytotoxicity 5/272 44/18670 0.000431736 0.006184322 0.005017469 5 GO:0001562 BP GO:0001562 response to protozoan 4/272 25/18670 0.000437945 0.006245141 0.005066812 4 GO:0043902 BP GO:0043902 positive regulation of multi-organism process 10/272 188/18670 0.00044876 0.00636347 0.005162816 10 GO:0007159 BP GO:0007159 leukocyte cell-cell adhesion 14/272 337/18670 0.000450246 0.00636347 0.005162816 14 GO:0070661 BP GO:0070661 leukocyte proliferation 13/272 298/18670 0.000452902 0.006372691 0.005170296 13 GO:0002730 BP GO:0002730 regulation of dendritic cell cytokine production 3/272 11/18670 0.000462764 0.006414468 0.005204191 3 GO:0045351 BP GO:0045351 type I interferon biosynthetic process 3/272 11/18670 0.000462764 0.006414468 0.005204191 3 GO:0072608 BP GO:0072608 interleukin-10 secretion 3/272 11/18670 0.000462764 0.006414468 0.005204191 3 GO:0030595 BP GO:0030595 leukocyte chemotaxis 11/272 224/18670 0.00046394 0.006414468 0.005204191 11 GO:0002702 BP GO:0002702 positive regulation of production of molecular mediator of immune response 7/272 95/18670 0.000478303 0.006584437 0.005342091 7 GO:0032755 BP GO:0032755 positive regulation of interleukin-6 production 7/272 96/18670 0.000509611 0.006985189 0.005667228 7 GO:0002715 BP GO:0002715 regulation of natural killer cell mediated immunity 5/272 46/18670 0.000532181 0.007201425 0.005842666 5 GO:0043330 BP GO:0043330 response to exogenous dsRNA 5/272 46/18670 0.000532181 0.007201425 0.005842666 5 GO:0050706 BP GO:0050706 regulation of interleukin-1 beta secretion 5/272 46/18670 0.000532181 0.007201425 0.005842666 5 GO:0034121 BP GO:0034121 regulation of toll-like receptor signaling pathway 6/272 70/18670 0.000543549 0.007324098 0.005942192 6 GO:1903037 BP GO:1903037 regulation of leukocyte cell-cell adhesion 13/272 304/18670 0.00054628 0.007329836 0.005946848 13 GO:0032680 BP GO:0032680 regulation of tumor necrosis factor production 9/272 160/18670 0.000575891 0.007694673 0.006242848 9 GO:0042531 BP GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 6/272 71/18670 0.000586578 0.007804679 0.006332098 6 GO:0050708 BP GO:0050708 regulation of protein secretion 17/272 472/18670 0.000590831 0.007828505 0.006351429 17 GO:0032635 BP GO:0032635 interleukin-6 production 9/272 161/18670 0.000602374 0.007858425 0.006375703 9 GO:0002429 BP GO:0002429 immune response-activating cell surface receptor signaling pathway 17/272 473/18670 0.000604971 0.007858425 0.006375703 17 GO:0002371 BP GO:0002371 dendritic cell cytokine production 3/272 12/18670 0.000610387 0.007858425 0.006375703 3 GO:0006216 BP GO:0006216 cytidine catabolic process 3/272 12/18670 0.000610387 0.007858425 0.006375703 3 GO:0009972 BP GO:0009972 cytidine deamination 3/272 12/18670 0.000610387 0.007858425 0.006375703 3 GO:0016554 BP GO:0016554 cytidine to uridine editing 3/272 12/18670 0.000610387 0.007858425 0.006375703 3 GO:0046087 BP GO:0046087 cytidine metabolic process 3/272 12/18670 0.000610387 0.007858425 0.006375703 3 GO:0072527 BP GO:0072527 pyrimidine-containing compound metabolic process 7/272 99/18670 0.000613436 0.007865838 0.006381717 7 GO:0032640 BP GO:0032640 tumor necrosis factor production 9/272 163/18670 0.000658336 0.008407664 0.006821313 9 GO:0010498 BP GO:0010498 proteasomal protein catabolic process 17/272 477/18670 0.000664484 0.008452233 0.006857472 17 GO:2000108 BP GO:2000108 positive regulation of leukocyte apoptotic process 4/272 28/18670 0.00068494 0.008657487 0.007023999 4 GO:0032611 BP GO:0032611 interleukin-1 beta production 7/272 101/18670 0.00069151 0.008657487 0.007023999 7 GO:0048661 BP GO:0048661 positive regulation of smooth muscle cell proliferation 7/272 101/18670 0.00069151 0.008657487 0.007023999 7 GO:0050830 BP GO:0050830 defense response to Gram-positive bacterium 7/272 101/18670 0.00069151 0.008657487 0.007023999 7 GO:2001242 BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 9/272 165/18670 0.000718477 0.008959827 0.007269293 9 GO:0032677 BP GO:0032677 regulation of interleukin-8 production 6/272 74/18670 0.000731676 0.009088792 0.007373926 6 GO:0043301 BP GO:0043301 negative regulation of leukocyte degranulation 3/272 13/18670 0.000784981 0.009637987 0.007819499 3 GO:0045779 BP GO:0045779 negative regulation of bone resorption 3/272 13/18670 0.000784981 0.009637987 0.007819499 3 GO:0060340 BP GO:0060340 positive regulation of type I interferon-mediated signaling pathway 3/272 13/18670 0.000784981 0.009637987 0.007819499 3 GO:0051249 BP GO:0051249 regulation of lymphocyte activation 17/272 485/18670 0.000798711 0.009768845 0.007925666 17 GO:0019674 BP GO:0019674 NAD metabolic process 6/272 76/18670 0.000842836 0.010269031 0.008331478 6 GO:0048660 BP GO:0048660 regulation of smooth muscle cell proliferation 9/272 169/18670 0.000852227 0.010304498 0.008360253 9 GO:0051100 BP GO:0051100 negative regulation of binding 9/272 169/18670 0.000852227 0.010304498 0.008360253 9 GO:0002828 BP GO:0002828 regulation of type 2 immune response 4/272 30/18670 0.000896059 0.010712286 0.0086911 4 GO:0046640 BP GO:0046640 regulation of alpha-beta T cell proliferation 4/272 30/18670 0.000896059 0.010712286 0.0086911 4 GO:0090200 BP GO:0090200 positive regulation of release of cytochrome c from mitochondria 4/272 30/18670 0.000896059 0.010712286 0.0086911 4 GO:0048659 BP GO:0048659 smooth muscle cell proliferation 9/272 171/18670 0.000926322 0.011032603 0.00895098 9 GO:0032731 BP GO:0032731 positive regulation of interleukin-1 beta production 5/272 52/18670 0.000939909 0.011152657 0.009048382 5 GO:0016579 BP GO:0016579 protein deubiquitination 12/272 283/18670 0.000953308 0.011269585 0.009143248 12 GO:0046133 BP GO:0046133 pyrimidine ribonucleoside catabolic process 3/272 14/18670 0.000988344 0.011640491 0.009444172 3 GO:0070665 BP GO:0070665 positive regulation of leukocyte proliferation 8/272 139/18670 0.000996559 0.011693939 0.009487536 8 GO:0002724 BP GO:0002724 regulation of T cell cytokine production 4/272 31/18670 0.001017132 0.011851948 0.009615731 4 GO:0031638 BP GO:0031638 zymogen activation 5/272 53/18670 0.001025632 0.011851948 0.009615731 5 GO:0050702 BP GO:0050702 interleukin-1 beta secretion 5/272 53/18670 0.001025632 0.011851948 0.009615731 5 GO:0050704 BP GO:0050704 regulation of interleukin-1 secretion 5/272 53/18670 0.001025632 0.011851948 0.009615731 5 GO:0060071 BP GO:0060071 "Wnt signaling pathway, planar cell polarity pathway" 7/272 108/18670 0.00102866 0.011851948 0.009615731 7 GO:0097529 BP GO:0097529 myeloid leukocyte migration 10/272 210/18670 0.001054527 0.012106127 0.009821952 10 GO:0042180 BP GO:0042180 cellular ketone metabolic process 11/272 248/18670 0.001073473 0.012279297 0.009962449 11 GO:0002695 BP GO:0002695 negative regulation of leukocyte activation 9/272 175/18670 0.001090221 0.012426179 0.010081617 9 GO:0002791 BP GO:0002791 regulation of peptide secretion 17/272 500/18670 0.00111352 0.012551691 0.010183448 17 GO:0032655 BP GO:0032655 regulation of interleukin-12 production 5/272 54/18670 0.001117022 0.012551691 0.010183448 5 GO:0043392 BP GO:0043392 negative regulation of DNA binding 5/272 54/18670 0.001117022 0.012551691 0.010183448 5 GO:0070206 BP GO:0070206 protein trimerization 5/272 54/18670 0.001117022 0.012551691 0.010183448 5 GO:0090175 BP GO:0090175 regulation of establishment of planar polarity 7/272 110/18670 0.001145491 0.012826278 0.010406225 7 GO:0042742 BP GO:0042742 defense response to bacterium 13/272 330/18670 0.001161443 0.012959257 0.010514114 13 GO:0032613 BP GO:0032613 interleukin-10 production 5/272 55/18670 0.001214307 0.013401827 0.010873181 5 GO:0030099 BP GO:0030099 myeloid cell differentiation 15/272 416/18670 0.001215047 0.013401827 0.010873181 15 GO:0042976 BP GO:0042976 activation of Janus kinase activity 3/272 15/18670 0.001222179 0.013401827 0.010873181 3 GO:0046851 BP GO:0046851 negative regulation of bone remodeling 3/272 15/18670 0.001222179 0.013401827 0.010873181 3 GO:0051770 BP GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 3/272 15/18670 0.001222179 0.013401827 0.010873181 3 GO:0032637 BP GO:0032637 interleukin-8 production 6/272 82/18670 0.001255584 0.013720811 0.011131979 6 GO:0050868 BP GO:0050868 negative regulation of T cell activation 7/272 112/18670 0.001272486 0.013857899 0.011243201 7 GO:0046633 BP GO:0046633 alpha-beta T cell proliferation 4/272 33/18670 0.001292938 0.013984835 0.011346187 4 GO:0070232 BP GO:0070232 regulation of T cell apoptotic process 4/272 33/18670 0.001292938 0.013984835 0.011346187 4 GO:0043161 BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 15/272 419/18670 0.001304437 0.014061394 0.011408301 15 GO:0032615 BP GO:0032615 interleukin-12 production 5/272 56/18670 0.001317718 0.014108902 0.011446845 5 GO:0070936 BP GO:0070936 protein K48-linked ubiquitination 5/272 56/18670 0.001317718 0.014108902 0.011446845 5 GO:1905330 BP GO:1905330 regulation of morphogenesis of an epithelium 9/272 180/18670 0.001327314 0.014163953 0.011491509 9 GO:0010565 BP GO:0010565 regulation of cellular ketone metabolic process 9/272 181/18670 0.001379377 0.014670299 0.011902318 9 GO:0002688 BP GO:0002688 regulation of leukocyte chemotaxis 7/272 114/18670 0.001410244 0.014948586 0.012128098 7 GO:0043154 BP GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 6/272 84/18670 0.001422775 0.015031313 0.012195216 6 GO:0002830 BP GO:0002830 positive regulation of type 2 immune response 3/272 16/18670 0.001488099 0.015617673 0.012670942 3 GO:0097067 BP GO:0097067 cellular response to thyroid hormone stimulus 3/272 16/18670 0.001488099 0.015617673 0.012670942 3 GO:0070646 BP GO:0070646 protein modification by small protein removal 12/272 299/18670 0.00152324 0.015933893 0.012927498 12 GO:1902041 BP GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 5/272 58/18670 0.001543846 0.016061209 0.013030792 5 GO:0042098 BP GO:0042098 T cell proliferation 9/272 184/18670 0.001545513 0.016061209 0.013030792 9 GO:0032760 BP GO:0032760 positive regulation of tumor necrosis factor production 6/272 86/18670 0.001606427 0.016535235 0.013415379 6 GO:0032735 BP GO:0032735 positive regulation of interleukin-12 production 4/272 35/18670 0.001617125 0.016535235 0.013415379 4 GO:0042092 BP GO:0042092 type 2 immune response 4/272 35/18670 0.001617125 0.016535235 0.013415379 4 GO:0045070 BP GO:0045070 positive regulation of viral genome replication 4/272 35/18670 0.001617125 0.016535235 0.013415379 4 GO:0070423 BP GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 4/272 35/18670 0.001617125 0.016535235 0.013415379 4 GO:0001836 BP GO:0001836 release of cytochrome c from mitochondria 5/272 59/18670 0.001667031 0.016936611 0.013741024 5 GO:0032732 BP GO:0032732 positive regulation of interleukin-1 production 5/272 59/18670 0.001667031 0.016936611 0.013741024 5 GO:0002690 BP GO:0002690 positive regulation of leukocyte chemotaxis 6/272 87/18670 0.001704745 0.017264613 0.014007139 6 GO:0060326 BP GO:0060326 cell chemotaxis 12/272 304/18670 0.001750399 0.017578156 0.014261522 12 GO:0002418 BP GO:0002418 immune response to tumor cell 3/272 17/18670 0.001787625 0.017578156 0.014261522 3 GO:0045091 BP GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 3/272 17/18670 0.001787625 0.017578156 0.014261522 3 GO:2001267 BP GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 3/272 17/18670 0.001787625 0.017578156 0.014261522 3 GO:0042267 BP GO:0042267 natural killer cell mediated cytotoxicity 5/272 60/18670 0.00179728 0.017578156 0.014261522 5 GO:0002755 BP GO:0002755 MyD88-dependent toll-like receptor signaling pathway 4/272 36/18670 0.001798667 0.017578156 0.014261522 4 GO:0030224 BP GO:0030224 monocyte differentiation 4/272 36/18670 0.001798667 0.017578156 0.014261522 4 GO:0035872 BP GO:0035872 "nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway" 4/272 36/18670 0.001798667 0.017578156 0.014261522 4 GO:1903131 BP GO:1903131 mononuclear cell differentiation 4/272 36/18670 0.001798667 0.017578156 0.014261522 4 GO:0032088 BP GO:0032088 negative regulation of NF-kappaB transcription factor activity 6/272 88/18670 0.001807565 0.017578156 0.014261522 6 GO:0070098 BP GO:0070098 chemokine-mediated signaling pathway 6/272 88/18670 0.001807565 0.017578156 0.014261522 6 GO:1903321 BP GO:1903321 negative regulation of protein modification by small protein conjugation or removal 6/272 88/18670 0.001807565 0.017578156 0.014261522 6 GO:1903557 BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 6/272 88/18670 0.001807565 0.017578156 0.014261522 6 GO:0050701 BP GO:0050701 interleukin-1 secretion 5/272 61/18670 0.00193483 0.018758412 0.015219089 5 GO:0050714 BP GO:0050714 positive regulation of protein secretion 11/272 268/18670 0.001988268 0.019217911 0.01559189 11 GO:2001236 BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 8/272 155/18670 0.001995991 0.019234095 0.01560502 8 GO:0050731 BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 9/272 192/18670 0.002068216 0.019869866 0.016120835 9 GO:0006521 BP GO:0006521 regulation of cellular amino acid metabolic process 5/272 62/18670 0.002079921 0.019922131 0.016163238 5 GO:0039535 BP GO:0039535 regulation of RIG-I signaling pathway 3/272 18/18670 0.002122192 0.020205301 0.01639298 3 GO:0039692 BP GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 3/272 18/18670 0.002122192 0.020205301 0.01639298 3 GO:1903320 BP GO:1903320 regulation of protein modification by small protein conjugation or removal 10/272 231/18670 0.00214119 0.020325329 0.016490361 10 GO:0009116 BP GO:0009116 nucleoside metabolic process 7/272 123/18670 0.002180188 0.020511833 0.016641676 7 GO:0042089 BP GO:0042089 cytokine biosynthetic process 7/272 123/18670 0.002180188 0.020511833 0.016641676 7 GO:0071621 BP GO:0071621 granulocyte chemotaxis 7/272 123/18670 0.002180188 0.020511833 0.016641676 7 GO:0001736 BP GO:0001736 establishment of planar polarity 7/272 124/18670 0.002282526 0.021223489 0.017219057 7 GO:0007164 BP GO:0007164 establishment of tissue polarity 7/272 124/18670 0.002282526 0.021223489 0.017219057 7 GO:0042107 BP GO:0042107 cytokine metabolic process 7/272 124/18670 0.002282526 0.021223489 0.017219057 7 GO:0051101 BP GO:0051101 regulation of DNA binding 7/272 124/18670 0.002282526 0.021223489 0.017219057 7 GO:0032943 BP GO:0032943 mononuclear cell proliferation 11/272 274/18670 0.00236173 0.021895924 0.017764617 11 GO:0002228 BP GO:0002228 natural killer cell mediated immunity 5/272 64/18670 0.002393685 0.022063533 0.017900602 5 GO:0046782 BP GO:0046782 regulation of viral transcription 5/272 64/18670 0.002393685 0.022063533 0.017900602 5 GO:0022407 BP GO:0022407 regulation of cell-cell adhesion 14/272 403/18670 0.002467467 0.022677875 0.018399031 14 GO:0002544 BP GO:0002544 chronic inflammatory response 3/272 19/18670 0.002493152 0.02271697 0.018430749 3 GO:0002726 BP GO:0002726 positive regulation of T cell cytokine production 3/272 19/18670 0.002493152 0.02271697 0.018430749 3 GO:0034138 BP GO:0034138 toll-like receptor 3 signaling pathway 3/272 19/18670 0.002493152 0.02271697 0.018430749 3 GO:0031331 BP GO:0031331 positive regulation of cellular catabolic process 13/272 361/18670 0.002562684 0.023218909 0.018837983 13 GO:0002548 BP GO:0002548 monocyte chemotaxis 5/272 65/18670 0.002562842 0.023218909 0.018837983 5 GO:0050866 BP GO:0050866 negative regulation of cell activation 9/272 199/18670 0.002633367 0.023722679 0.019246701 9 GO:0061013 BP GO:0061013 regulation of mRNA catabolic process 9/272 199/18670 0.002633367 0.023722679 0.019246701 9 GO:0031146 BP GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 6/272 95/18670 0.002664551 0.02388576 0.019379013 6 GO:0002369 BP GO:0002369 T cell cytokine production 4/272 40/18670 0.002666492 0.02388576 0.019379013 4 GO:0002687 BP GO:0002687 positive regulation of leukocyte migration 7/272 128/18670 0.002729417 0.024380747 0.019780606 7 GO:0033002 BP GO:0033002 muscle cell proliferation 10/272 239/18670 0.00273954 0.024402628 0.019798359 10 GO:1903038 BP GO:1903038 negative regulation of leukocyte cell-cell adhesion 7/272 129/18670 0.002850963 0.025324198 0.020546047 7 GO:0032495 BP GO:0032495 response to muramyl dipeptide 3/272 20/18670 0.002901774 0.025490722 0.020681152 3 GO:0034104 BP GO:0034104 negative regulation of tissue remodeling 3/272 20/18670 0.002901774 0.025490722 0.020681152 3 GO:0051767 BP GO:0051767 nitric-oxide synthase biosynthetic process 3/272 20/18670 0.002901774 0.025490722 0.020681152 3 GO:0051769 BP GO:0051769 regulation of nitric-oxide synthase biosynthetic process 3/272 20/18670 0.002901774 0.025490722 0.020681152 3 GO:0050870 BP GO:0050870 positive regulation of T cell activation 9/272 202/18670 0.0029102 0.025494312 0.020684064 9 GO:0042108 BP GO:0042108 positive regulation of cytokine biosynthetic process 5/272 67/18670 0.002926914 0.025570293 0.020745709 5 GO:1904951 BP GO:1904951 positive regulation of establishment of protein localization 15/272 456/18670 0.002944018 0.02562716 0.020791847 15 GO:1990868 BP GO:1990868 response to chemokine 6/272 97/18670 0.0029576 0.02562716 0.020791847 6 GO:1990869 BP GO:1990869 cellular response to chemokine 6/272 97/18670 0.0029576 0.02562716 0.020791847 6 GO:0032946 BP GO:0032946 positive regulation of mononuclear cell proliferation 7/272 131/18670 0.003106467 0.026777387 0.02172505 7 GO:0031396 BP GO:0031396 regulation of protein ubiquitination 9/272 204/18670 0.003107187 0.026777387 0.02172505 9 GO:0002440 BP GO:0002440 production of molecular mediator of immune response 11/272 286/18670 0.003279233 0.02818368 0.022866005 11 GO:0039531 BP GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 3/272 21/18670 0.00334925 0.028630687 0.023228671 3 GO:1904469 BP GO:1904469 positive regulation of tumor necrosis factor secretion 3/272 21/18670 0.00334925 0.028630687 0.023228671 3 GO:0048872 BP GO:0048872 homeostasis of number of cells 10/272 246/18670 0.003366641 0.028702191 0.023286683 10 GO:0051098 BP GO:0051098 regulation of binding 13/272 373/18670 0.00338718 0.02880009 0.02336611 13 GO:0071456 BP GO:0071456 cellular response to hypoxia 9/272 207/18670 0.003422235 0.029020551 0.023544975 9 GO:0002793 BP GO:0002793 positive regulation of peptide secretion 11/272 288/18670 0.003456763 0.029235387 0.023719276 11 GO:0032649 BP GO:0032649 regulation of interferon-gamma production 6/272 101/18670 0.003615182 0.030494106 0.024740501 6 GO:0032944 BP GO:0032944 regulation of mononuclear cell proliferation 9/272 209/18670 0.003645856 0.030671486 0.024884413 9 GO:0050921 BP GO:0050921 positive regulation of chemotaxis 7/272 135/18670 0.003669658 0.030790272 0.024980786 7 GO:0070266 BP GO:0070266 necroptotic process 4/272 44/18670 0.003785009 0.03167455 0.02569822 4 GO:0006925 BP GO:0006925 inflammatory cell apoptotic process 3/272 22/18670 0.003836695 0.03193898 0.025912757 3 GO:0032656 BP GO:0032656 regulation of interleukin-13 production 3/272 22/18670 0.003836695 0.03193898 0.025912757 3 GO:0046425 BP GO:0046425 regulation of JAK-STAT cascade 7/272 137/18670 0.003978816 0.033035597 0.026802465 7 GO:0002833 BP GO:0002833 positive regulation of response to biotic stimulus 4/272 45/18670 0.004107451 0.034014825 0.027596934 4 GO:0046631 BP GO:0046631 alpha-beta T cell activation 7/272 138/18670 0.00414061 0.034200363 0.027747465 7 GO:0030593 BP GO:0030593 neutrophil chemotaxis 6/272 104/18670 0.004175373 0.034309266 0.027835819 6 GO:0071887 BP GO:0071887 leukocyte apoptotic process 6/272 104/18670 0.004175373 0.034309266 0.027835819 6 GO:0050715 BP GO:0050715 positive regulation of cytokine secretion 7/272 139/18670 0.00430734 0.035302426 0.028641591 7 GO:0002347 BP GO:0002347 response to tumor cell 3/272 23/18670 0.00436515 0.03550173 0.028803291 3 GO:0010499 BP GO:0010499 proteasomal ubiquitin-independent protein catabolic process 3/272 23/18670 0.00436515 0.03550173 0.028803291 3 GO:0042454 BP GO:0042454 ribonucleoside catabolic process 3/272 23/18670 0.00436515 0.03550173 0.028803291 3 GO:0050730 BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 10/272 256/18670 0.004455104 0.036140895 0.029321858 10 GO:0048863 BP GO:0048863 stem cell differentiation 10/272 257/18670 0.004577632 0.037040381 0.03005163 10 GO:0001738 BP GO:0001738 morphogenesis of a polarized epithelium 7/272 141/18670 0.004655984 0.037400083 0.030343463 7 GO:0097530 BP GO:0097530 granulocyte migration 7/272 141/18670 0.004655984 0.037400083 0.030343463 7 GO:0036294 BP GO:0036294 cellular response to decreased oxygen levels 9/272 217/18670 0.004657369 0.037400083 0.030343463 9 GO:0048524 BP GO:0048524 positive regulation of viral process 6/272 107/18670 0.004797276 0.0381201 0.030927629 6 GO:1903039 BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 9/272 218/18670 0.004797782 0.0381201 0.030927629 9 GO:0002832 BP GO:0002832 negative regulation of response to biotic stimulus 4/272 47/18670 0.004806969 0.0381201 0.030927629 4 GO:0006953 BP GO:0006953 acute-phase response 4/272 47/18670 0.004806969 0.0381201 0.030927629 4 GO:0070231 BP GO:0070231 T cell apoptotic process 4/272 47/18670 0.004806969 0.0381201 0.030927629 4 GO:0022408 BP GO:0022408 negative regulation of cell-cell adhesion 8/272 181/18670 0.005139937 0.040659202 0.032987654 8 GO:0090199 BP GO:0090199 regulation of release of cytochrome c from mitochondria 4/272 48/18670 0.005184944 0.040913457 0.033193937 4 GO:0034504 BP GO:0034504 protein localization to nucleus 10/272 262/18670 0.005230648 0.041171934 0.033403645 10 GO:0031397 BP GO:0031397 negative regulation of protein ubiquitination 5/272 77/18670 0.005325318 0.041710622 0.033840693 5 GO:0061418 BP GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 5/272 77/18670 0.005325318 0.041710622 0.033840693 5 GO:0032616 BP GO:0032616 interleukin-13 production 3/272 25/18670 0.005548899 0.043191643 0.035042277 3 GO:1903306 BP GO:1903306 negative regulation of regulated secretory pathway 3/272 25/18670 0.005548899 0.043191643 0.035042277 3 GO:0043124 BP GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 4/272 49/18670 0.005582316 0.043191643 0.035042277 4 GO:0097300 BP GO:0097300 programmed necrotic cell death 4/272 49/18670 0.005582316 0.043191643 0.035042277 4 GO:2001238 BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 4/272 49/18670 0.005582316 0.043191643 0.035042277 4 GO:1904892 BP GO:1904892 regulation of STAT cascade 7/272 146/18670 0.005620602 0.043302375 0.035132116 7 GO:0072332 BP GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 5/272 78/18670 0.005623862 0.043302375 0.035132116 5 GO:1901657 BP GO:1901657 glycosyl compound metabolic process 7/272 147/18670 0.005830235 0.044782962 0.036333346 7 GO:1903532 BP GO:1903532 positive regulation of secretion by cell 13/272 399/18670 0.005919945 0.045361048 0.036802359 13 GO:0071260 BP GO:0071260 cellular response to mechanical stimulus 5/272 79/18670 0.005934024 0.045361048 0.036802359 5 GO:0080111 BP GO:0080111 DNA demethylation 3/272 26/18670 0.006205927 0.047212552 0.038304523 3 GO:0097066 BP GO:0097066 response to thyroid hormone 3/272 26/18670 0.006205927 0.047212552 0.038304523 3 GO:0045785 BP GO:0045785 positive regulation of cell adhesion 13/272 403/18670 0.006417571 0.04870615 0.03951631 13 GO:0000731 BP GO:0000731 DNA synthesis involved in DNA repair 4/272 51/18670 0.006436948 0.048736893 0.039541253 4 GO:0042035 BP GO:0042035 regulation of cytokine biosynthetic process 6/272 114/18670 0.006510111 0.049173763 0.039895694 6 GO:0031145 BP GO:0031145 anaphase-promoting complex-dependent catabolic process 5/272 81/18670 0.006590127 0.0495428 0.040195102 5 GO:0033238 BP GO:0033238 regulation of cellular amine metabolic process 5/272 81/18670 0.006590127 0.0495428 0.040195102 5 GO:0001666 BP GO:0001666 response to hypoxia 12/272 359/18670 0.006621541 0.04966156 0.040291455 12 GO:0042611 CC GO:0042611 MHC protein complex 7/278 25/19717 3.97E-08 1.14E-05 9.66E-06 7 GO:0071556 CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 7/278 29/19717 1.23E-07 1.18E-05 9.96E-06 7 GO:0098553 CC GO:0098553 lumenal side of endoplasmic reticulum membrane 7/278 29/19717 1.23E-07 1.18E-05 9.96E-06 7 GO:0055038 CC GO:0055038 recycling endosome membrane 10/278 81/19717 2.06E-07 1.48E-05 1.25E-05 10 GO:0010008 CC GO:0010008 endosome membrane 22/278 479/19717 1.34E-06 7.71E-05 6.51E-05 22 GO:0031901 CC GO:0031901 early endosome membrane 11/278 149/19717 8.88E-06 0.000389583 0.000328924 11 GO:0030176 CC GO:0030176 integral component of endoplasmic reticulum membrane 11/278 150/19717 9.47E-06 0.000389583 0.000328924 11 GO:0030670 CC GO:0030670 phagocytic vesicle membrane 8/278 76/19717 1.16E-05 0.000418263 0.000353139 8 GO:0031227 CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 11/278 158/19717 1.55E-05 0.000495499 0.000418349 11 GO:0012507 CC GO:0012507 ER to Golgi transport vesicle membrane 7/278 62/19717 2.60E-05 0.000750103 0.000633311 7 GO:0031904 CC GO:0031904 endosome lumen 5/278 34/19717 0.000107001 0.002598701 0.002194079 5 GO:0045335 CC GO:0045335 phagocytic vesicle 9/278 132/19717 0.000108279 0.002598701 0.002194079 9 GO:0005769 CC GO:0005769 early endosome 15/278 350/19717 0.000143621 0.003181765 0.002686358 15 GO:0055037 CC GO:0055037 recycling endosome 10/278 176/19717 0.000205385 0.004225064 0.003567214 10 GO:0030662 CC GO:0030662 coated vesicle membrane 10/278 182/19717 0.000269129 0.005167278 0.004362723 10 GO:0033655 CC GO:0033655 host cell cytoplasm part 3/278 10/19717 0.000309207 0.005565732 0.004699138 3 GO:0030134 CC GO:0030134 COPII-coated ER to Golgi transport vesicle 7/278 93/19717 0.000346256 0.005865988 0.004952644 7 GO:0019774 CC GO:0019774 "proteasome core complex, beta-subunit complex" 3/278 11/19717 0.000420733 0.006377425 0.005384449 3 GO:0030430 CC GO:0030430 host cell cytoplasm 3/278 11/19717 0.000420733 0.006377425 0.005384449 3 GO:0030666 CC GO:0030666 endocytic vesicle membrane 9/278 167/19717 0.000622884 0.008969535 0.007572963 9 GO:0033646 CC GO:0033646 host intracellular part 3/278 14/19717 0.000899507 0.01126339 0.00950966 3 GO:0043656 CC GO:0043656 intracellular region of host 3/278 14/19717 0.000899507 0.01126339 0.00950966 3 GO:0061702 CC GO:0061702 inflammasome complex 3/278 14/19717 0.000899507 0.01126339 0.00950966 3 GO:0030660 CC GO:0030660 Golgi-associated vesicle membrane 7/278 114/19717 0.001171267 0.014055207 0.011866786 7 GO:0033643 CC GO:0033643 host cell part 3/278 16/19717 0.001355274 0.015612757 0.013181823 3 GO:0000502 CC GO:0000502 proteasome complex 5/278 63/19717 0.001939026 0.021478445 0.018134213 5 GO:1905369 CC GO:1905369 endopeptidase complex 5/278 64/19717 0.002079519 0.022181541 0.018727836 5 GO:0005839 CC GO:0005839 proteasome core complex 3/278 20/19717 0.00264639 0.027220011 0.022981807 3 GO:0009897 CC GO:0009897 external side of plasma membrane 13/278 393/19717 0.004008118 0.039804755 0.033607085 13 GO:0005765 CC GO:0005765 lysosomal membrane 12/278 354/19717 0.004629285 0.043968367 0.037122415 12 GO:0098852 CC GO:0098852 lytic vacuole membrane 12/278 355/19717 0.004732706 0.043968367 0.037122415 12 GO:0003725 MF GO:0003725 double-stranded RNA binding 11/270 75/17697 1.76E-08 8.33E-06 7.45E-06 11 GO:0042605 MF GO:0042605 peptide antigen binding 7/270 31/17697 3.42E-07 8.11E-05 7.26E-05 7 GO:0042379 MF GO:0042379 chemokine receptor binding 8/270 66/17697 7.07E-06 0.000838482 0.000750407 8 GO:0005125 MF GO:0005125 cytokine activity 14/270 220/17697 7.53E-06 0.000838482 0.000750407 14 GO:0008009 MF GO:0008009 chemokine activity 7/270 49/17697 8.84E-06 0.000838482 0.000750407 7 GO:0003724 MF GO:0003724 RNA helicase activity 8/270 78/17697 2.47E-05 0.001686241 0.001509116 8 GO:0004842 MF GO:0004842 ubiquitin-protein transferase activity 18/270 382/17697 2.49E-05 0.001686241 0.001509116 18 GO:0005126 MF GO:0005126 cytokine receptor binding 15/270 286/17697 3.54E-05 0.002099066 0.001878578 15 GO:0019787 MF GO:0019787 ubiquitin-like protein transferase activity 18/270 407/17697 5.69E-05 0.00299627 0.002681538 18 GO:0016504 MF GO:0016504 peptidase activator activity 5/270 38/17697 0.000264829 0.012552898 0.011234328 5 GO:0043028 MF GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 5/270 42/17697 0.000427073 0.018071181 0.016172964 5 GO:0048018 MF GO:0048018 receptor ligand activity 18/270 482/17697 0.000457498 0.018071181 0.016172964 18 GO:0003727 MF GO:0003727 single-stranded RNA binding 7/270 95/17697 0.000627307 0.022872564 0.020470006 7 GO:0004126 MF GO:0004126 cytidine deaminase activity 3/270 12/17697 0.000697734 0.023623265 0.021141852 3 GO:0019239 MF GO:0019239 deaminase activity 4/270 32/17697 0.001361235 0.040624656 0.036357398 4 GO:0097153 MF GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process 3/270 15/17697 0.001394946 0.040624656 0.036357398 3 GO:0043621 MF GO:0043621 protein self-association 5/270 56/17697 0.001612626 0.040624656 0.036357398 5 GO:0008656 MF GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/270 16/17697 0.001697597 0.040624656 0.036357398 3 GO:0050700 MF GO:0050700 CARD domain binding 3/270 16/17697 0.001697597 0.040624656 0.036357398 3 GO:0016814 MF GO:0016814 "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines" 4/270 34/17697 0.00171412 0.040624656 0.036357398 4